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As James Kildare, M.D. (Richard Chamberlain) lends his hard-won experience and insights into the cases that come into his care, aided by the sage counsel of Dr. Leonard Gillespie (Raymond Massey), the series ups the ante with some surprising complications while continuing to deliver an all-star line-up of guest stars. This 8-Disc, 34-Episode Collection starts with a stand-out performance by Walter Matthau as a salesman facing death. Kim Darby, Lee Marvin, Ron Howard, Robert Young, and Robert Culp all pay visits to Blair General, while Leslie Nielsen and Angie Dickinson guest for a multi-part arc that paints a prescient portrait of sexual addiction. And legendary tunesmiths Burt Bacharach and Hal David pen the title theme for Rome Will Never Leave You, a special three-part episode that sees Kildare and Gillespie battling cancer and heartbreak in Rome along with Ramon Novarro, Mercedes McCambridge, Daniela Bianchi and Alida Valli.